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Sterile. Soothing relief for serious dry eye. Preservative- free. Bion Tears Lubricant Eye Drops is an advanced tear substitute especially formulated and packaged for persistent dry eye conditions requiring frequent therapy. Studies show that Bion Tears is the preferred choice of patients (Sjogren's syndrome) and physicians (corneal specialists) over four other brands. Moreover, Bion Tears has been clinically proven to be significantly more comfortable then Refresh Plus.